132016Nov

Elevated psa

Prostatitis is a disease in men with high morbidity and recurrence rates, prostatitis to men suffering is difficult to understand, infertility treatment, but we can from the formation of prostatitis or Symptoms and other related information can be learned. That for the prostatitis we understand how much? Today, Guangzhou Changan Hospital experts to bring you to come to know: psa high why?, hope that we see a certain understanding of prostatitis!In the prostate cancer examination, PSA index is often an important indicator of prostate cancer, for some male friends, PSA values tend to make them very frightened, fear of suffering from prostate cancer, in fact, PSA index and Can not diagnose prostate cancer, the diagnosis of prostate cancer also need other related checks. Many people will ask, why PSA will rise? PSA high reason why? To this end, Guangzhou Changan infertility hospital experts conducted the following answers.

Any cause of prostate damage or infection can cause elevated PSA, such as urinary tract infections, prostate stones, recent catheterization and urethral cystoscopy, recent prostate biopsy or prostate surgery. Sexual behavior can make PSA increased by 10%, blood PSA examination before the rectal examination and prostate massage will also increase the PSA value. Benign prostatic hyperplasia (BPH) also increases PSA, mainly due to the fact that more prostate cells produce more PSA. Proliferation of benign prostatic hyperplasia produced by the amount of PSA than the amount produced by prostate cancer is low, so benign prostatic hyperplasia, PSA density (PSA / prostate volume) lower than prostate cancer. Prostate will increase with age, so the PSA value will be gradually increased by age. The rate of change of the PSA value over a period of time is called the PSA rate. Most people think that the PSA rate of prostate hyperplasia rarely exceeds 0.7ng / ml.

Under normal circumstances, PSA produced in the prostate epithelial cells, directly secreted into the prostate ductal system. The presence of a blood-epithelial barrier between the normal prostate duct system and the prostate-induced PSA directly enters the bloodstream, maintaining a low concentration of PSA in the blood circulation. When this barrier is destroyed for some reason, the PSA enters the blood directly and causes an increase in PSA in the blood. There are two common causes: mechanical injury and invasive disease. The former include prostate biopsy, intrahepatic drug injection, urethral stricture for forced mechanical expansion and transurethral resection of the prostate, the latter mainly for prostate cancer. The higher the malignancy of cancer, the greater the normal prostate tissue damage, the higher the serum PSA. The longer the tumor in the body, the greater the tumor, the greater the damage to normal prostate tissue, the higher the serum PSA.

Experts point out that prostate cancer is manifested by elevated levels of malignant PSA, so it is also important to distinguish between benign and malignant PSA elevation. The current distinction between benign and malignant PSA elevation is often from the PSA density, PSA speed, the application of free PSA in the body to write this aspect, the distinction is still a certain degree of difficulty.

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